Not for any run-of-the-mill, mass-production stuff, but I don't buy hardly any of that to start with. All of my practical needs have been covered for some time, and I don't have any interest in cycling through this or that latest plastic gun, this or that budget 1911, etc.
But I have a number of collectible handguns with total production numbers ranging from the low single digits to the low triple digits (along with others originally produced in greater numbers but reduced by the long passage of time), and I have, by my estimation, certainly overpaid for a few of them. When it's (1) something I really want and (2) something I'm very unlikely to see again for years, or maybe ever, I'm willing to pay significantly more than my estimate of average fair market value to get it (to the extent that figure even can be determined for items that almost never change hands). Even so, what I paid then is somewhere between a very fair price and a screaming deal today in many cases, even accounting for inflation. I've found a number of good to great deals over the years as well, especially with the pricing of the guns I buy in Europe relative to their going rates here, so it evens out in the aggregate.