i'm relatively new to compensators, but run a comped 45 and 38 super. yes, the conventional wisdom is that slower powders produce more gas (larger charge of gunpowder) and this helps to run the comp. i've tried a couple of different loads in the 45 and with fast burning powders (231, Vit N320) there's little recoil compensation, but a heavier charge of a slower powder (Longshot) does have a noticeable effect on muzzle rise. bullet velocity was about the same for both powders.
i've run 3 powders through the 38 super with good results. Silhouette, Vit 3N38 and Vit N105. the 3N38 is the cleanest of the bunch (i think), and both it and N105 make lots of noise (compared to Silhouette) and feel more similar than Silhouette (to me). they all 3 have a pronounced effect on muzzle climb. Silhouette uses a lower powder charge (the fastest of the bunch, and the cheapest) and seems to work well for me. i like them all, and they do feel a bit different from one another. experienced shooters say that you have to find a powder and bullet weight that feels right for you. i can attest that the difference in gun "feel" gets pretty subjective when trying different loads in a compensated 1911 when tested at the same time, so i can't say that one is better than another, just a bit different. all these powders are likely much cleaner burning than #9. Silhouette is actually the old Winchester Action Pistol, and Winchester showed it in their loading manual for maximum velocity loads in 9X23, which i also use it for. a compensator has a greater effect for the 9X23 and 38 Super than for the 45 in my experience, but the 45 still benefits from reduced muzzle climb with a comp. i once asked some experienced comp shooters how many ports that a 45 could benefit from (it may not benefit from lots of ports like a 38 Super) and most suggested that 2 ports is all that is really needed for the 45. i have a 3 port comp on mine and have not yet made the plunge to cut one off to test their suggestion, and probably won't. its runs fine so i won't mess with it.
good luck! you'll have fun testing powders no matter what you try. a comped 38 Super (or 9X23) is a fun gun to play with, and a comped 45 isn't bad either.